Treponema pallidum, the causative agent of syphilis, is seen in this electron micrograph adhering to a surface with the end of its structure. Image: Public Health Image Library, CDC
When syphilis first descended upon Europe, it was seen as a new plague, and anxiety and blame coalesced around this mysterious scourge. Was it a punishment from God? Was it introduced by a hated Other? Was it caused by the stars’ alignment or the presence of “bad air”? The panic it provoked foreshadowed the hysteria that surrounded the emergence of HIV in the 1980s, as syphilitics were discriminated against, feared, or thought to have received punishment for their “unbridled lust.”
We now know that syphilis is not caused by supernatural forces, foreigners, or “bad air,” but rather by a species of spiral-shaped bacteria called Treponema pallidum, which can cause infections in the vagina, anus, urethra, or penis, as well as the lips and mouth. It is mostly spread by sexual contact – vaginal or anal intercourse, as well as oral sex – in which one person comes into contact with a syphilis sore. These sores can be hidden on the cervix or in the vagina, urethra, rectum, or mouth, making it not immediately apparent that one is infected with syphilis. Syphilis can also spread to a fetus during pregnancy. Sexually active people can reduce their risk of contracting syphilis by using latex barrier methods such as condoms or dental dams. Continue reading
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Tagged antibiotic, antibiotics, antigenic variation, arsenic, bacteria, chancre, Great Pox, gummatous syphilis, latent syphilis, lesion, lesions, malaria, malaria therapy, mercury, Neosalvarsan, Paul Ehrlich, penicillin, primary syphilis, Salvarsan, secondary syphilis, sexually transmitted disease, sexually transmitted diseases, sexually transmitted infection, sexually transmitted infections, spirochete, STD, STDs, STI, STIs, syphilis, T. pallidum, tertiary syphilis, Treponema pallidum, ulcer
Neisseria gonorrhoeae, the bacteria species that causes gonorrhea, is pictured here in a photograph taken with a scanning electron microscope. Projecting from the organism’s surface are many pili, powerful appendages that enable the bacteria to adhere to human cells. Image from the National Institute of Biomedical Imaging and Bioengineering.
April is STD Awareness Month, but this blog has sought to increase your awareness of sexually transmitted infections on a monthly basis. So far in 2011 we’ve pointed the spotlight at human papillomavirus, barrier methods, and herpes. This month’s installment will focus on gonorrhea, colloquially known as “the clap,” a common sexually transmitted infection caused by sneaky bacteria called Neisseria gonorrhoeae. It is spread by vaginal, anal, and oral sex, and can infect certain cells in the throat, mouth, rectum, urethra, or cervix. It can also be transmitted manually to infect the eye. If you are sexually active, you can reduce risk of transmission by consistently and correctly using latex barriers such as condoms and dental dams.
Four out of five females infected with gonorrhea do not experience symptoms – males, however, usually do, but they can be mild and therefore easy to overlook. Symptoms can appear within a month, and might include painful or frequent urination, vaginal or penile discharge, painful bowel movements, itching, or sore throat. Additionally, females can experience abdominal pain, fever, irregular menstruation, or bleeding between periods. In pregnant women, untreated gonorrhea infections can lead to complications such as premature labor or stillbirth. The infection can also be passed from mother to infant during delivery. Continue reading
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Tagged antibiotic resistant gonorrhea, antibiotics, antigenic variation, ARG, bacteria, bacterium, DGI, disseminated gonococcal infection, epididymitis, evolution, fimbriae, flagella, flagellum, GC, gonococci, gonococcus, gonorrhea, HIV, immune response, immune system, microbe, microorganism, N. gonorrhoeae, Neisseria gonorrhoeae, Opa protein, Opa proteins, pelvic inflammatory disease, PID, pili, pilus, retractile pili, sexually transmitted disease, sexually transmitted infection, STD, STI, sulfa drugs, sulfanilamide, sulfonamides, the clap, type IV pili